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体内药效学研究平台
展鸢生物疾病动物模型平台，覆盖肿瘤、神经、心血管、内分泌代谢、自身免疫等研究方向，提供模型构建、药效评价与检测分析一站式服务，支撑新药临床前研究。
常用疾病动物模型
肿瘤模型
- 多癌种人源细胞系衍生异种移植物(CDX)模型
- 临床样本异种移植瘤(PDX)模型
- 诱发性肿瘤模型
- 人源化动物肿瘤模型(PBMC/HSC)
代谢与消化道模型
- 多种糖尿病及并发症模型
- 酒精性/非酒精性脂肪肝
- 溃疡性结肠炎
- 高血压/高血脂/肥胖
- 肝纤维化/肝硬化/肝衰
- 肾性贫血
- 急性重症胰腺炎
- 骨质疏松/肺纤维化
自身免疫性疾病模型
- 类风湿性关节炎
- 消炎消肿
- 银屑病
- 放射性血小板减少症
- GVHD模型
- 红斑狼疮
- 多发性硬化症
- 哮喘/特应性皮炎/肺炎
心脑血管模型
- 缺血性脑卒中
- 心衰/心梗模型
- 肺栓塞/出血转化
- 颅脑损伤
- 血管钙化/动脉粥样硬化
- 高血压/心肌病
- 冠心病
- 单侧硬脑膜缺损模型
神经与镇痛类模型
- 阿尔兹海默症
- 血管性痴呆/老年性痴呆
- 帕金森氏症
- 抑郁/焦虑疾病
- 慢性压迫性神经损伤
- 坐骨神经阻滞
- 局部镇痛
- 肠道菌群调控
- 偏头痛/癫痫/三叉神经痛
眼科模型
- 糖尿病角膜病变
- 碱烧伤角膜损伤模型
- 急性高眼压
- 干眼症
- 青光眼
- 近视眼
